Cytotoxicity of CM and ZM extracts. The effect of CM and ZM extracts on cell viability was determined by the 3-(4,5)-dimethylthiahiazo-(-z-y1)-3,5-diphenytetrazoliumromide assay. When not indicated by fold lines, * and ** represent significant differences from the vehicle (dimethyl sulfoxide) treated group; *P<0.05, **P<0.001. CM, Chuan Maidong; ZM, Zhe Maidong; ee, ethanol extract; ae, aqueous extract.