Table 2.
Baseline Characteristics by Hospital and Outcome Groups of Children (N = 383) with Acute Bacterial Meningitis in Guatemala City, 2000-2007
| Variables | Alive N (%) | Major Morbidity N (%) | Dead N (%) | p-value* |
|---|---|---|---|---|
| Total subjects | 92 | 212 | 79 | |
| Hospital | ||||
| HGSDJ | 31 (34) | 61 (28) | 19 (24) | <0.0001 |
| Roosevelt | 21 (23) | 116 (55) | 52 (66) | |
| IGSS | 40 (43) | 35 (83) | 8 (10) | |
| Demographics | ||||
| Male | 57 (62) | 151 (71) | 37 (47) | 0.05 |
| Age under 12 months | 77 (84) | 145 (68) | 53 (67) | 0.01 |
| Wet season | 51 (55) | 96 (45) | 46 (58) | 0.08 |
| Received antibiotics prior to arrival | 28 (30) | 98 (46) | 36 (46) | 0.03 |
| Received Hib vaccine (if > 2 months old) | 0 (0) | 8 (4) | 4 (5) | 0.30 |
| Organism isolated | ||||
| Hib | 16 (17) | 68 (32) | 18 (23) | <0.0001** |
| Spn | 12 (13) | 40 (19) | 28 (35) | |
| Other non-contaminants§ | 14 (15) | 19 (9) | 5 (6) | |
| Testing negative | 35 (38) | 43 (20) | 12 (15) |
*
Chi-square test for p-values
**
Some children were positive for more than one organism: 4 had both Hib and Spn, 6 had both Hib and other non-contaminants, and 2 had both Spn and other non-contaminants. p-value only for children with only one organism isolated. 81 children did not get tested.
§
Other non-contaminant included N. meningitidis, Salmonella, E. coli, Pseudomonas, and Group B Streptococcus.