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. 2015 Jan 21;6(8):5760–5771. doi: 10.18632/oncotarget.3306

Figure 4. The distribution of the contribution of single nucleotide SMV to overall SMV in CRC patients.

Figure 4

A) A linear fit of the total SMV as a function of single nucleotide SMV distribution and B) total SMV as a function of single nucleotide as a fraction of total SMV. In both figures a clear set of outliers entirely consisting of 32% of the total African American (orange squares) CRC patient population is encircled. C) and D) show the same distributions with the binomial fit inflection point used as a cutoff between SMV-high (blue diamonds) and SMV-stable (orange square) patient groups.