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. 2015 Feb 28;6(8):5932–5946. doi: 10.18632/oncotarget.3465

Figure 1. Expression of miR-21 in culture media of ICC cell lines and serum samples.

Figure 1

(A) and (B) MiR-21 levels in the media of both HUCCT1 and RBE increased with increased cell counts and longer incubation intervals. (C) Serum levels of miR-21 in normal controls and ICC patients. Boxes represent interquartile range, and the horizontal line across each box indicates median value. (D) Serum miR-21 yielded an area under the curve (AUC) value of 0.9081, with 87.8% sensitivity and 90.5% specificity in distinguishing ICC patients from normal control subjects. (E) Comparison of serum miR-21 levels from all ICC patients (n=74). (F) Comparison of serum miR-21 in 17 ICC patients who underwent palliative resection. (G) Comparison of serum miR-21 levels in 57 ICC patients who underwent potentially curative surgeries.