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. 2015 Jan 21;6(8):5947–5962. doi: 10.18632/oncotarget.3335

Figure 7. GSK3α, and not GSK3β regulates intrinsic caspase-3/9 dependent survival pathway in prostate cancer cells.

Figure 7

(A) Western blot images showing the effect of GSK3α and GSK3β gene silencing in PC3 (left panel), DU145 (center panel) and LNCaP (right panel) cells on the levels of cleaved caspase-9 and cleaved caspase-3, important mediators of intrinsic apoptotic pathway. (B) Densitometry analysis of Western blot images showing the effect of GSK3α and GSK3β gene silencing in PC3, DU145 and LNCaP cells on the levels of cleaved caspase-9 and cleaved caspase-3, along with phosphorylated and total levels of GSK3α and GSK3β (n=3). Data is shown as Mean + SD; *,#,▲p<0.05 for PC3, DU145 and LNCaP cells, respectively.