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. 2015 Jan 21;6(8):6014–6028. doi: 10.18632/oncotarget.3338

Figure 7. The schematic plot for the regulatory relationship among miR-1236, AFP and PTEN in HCC.

Figure 7

miR-1236 down-regulates alpha-fetoprotein, thus causing PTEN accumulation, which inhibits the PI3K/Akt pathway and malignant phenotypes including proliferation, migration/invasion and vasculogenic mimicry.