Figure 2. Representative photographs of angiogenesis in mice in response to colorectal cancer cell fluid(colorectal cancer cell lines:DLD-1, HCT116, HT29).

A) Culture fluid alone, B) culture fluid plus the anti-VEGF mAb, C) culture fluid plus the anti- PROK1 mAb, D) culture fluid plus the anti-VEGF mAb and anti-PROK1 mAb.