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. 2015 Jan 31;6(8):6218–6234. doi: 10.18632/oncotarget.3358

Fig.1. WISP1 as an oncofetal gene was a marker of poor prognosis of ESCC patients after surgery.

Fig.1

A. WISP1, a downstream target gene of Wnt/β-catenin pathway was highly expressed at mRNA level in ESCC tissues compared with in matched normal tissues by bio-informatics analysis of the data from GSE17351 and GSE26886. B. The expression of WISP1 protein in 22-weeks fetal esophagus, normal adult esophagus, ESCC tissues and matched non-neoplastic tissues by IHC analysis. C. Kaplan–Meier analysis showed that overall survival of WISP1-positive ESCC patients was significantly poorer than those WISP1-negative patients after surgery. The grading of WISP1 expression was described in “Materials and Methods”.