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A–C, FGFR1, FGF2, and FGF9 mRNA in small-cell lung cancer (in situ hybridization, 200× original magnification). Brown dots in cells represent mRNA expression. A, FGFR1 mRNA ISH expression (score = 4); a, FGFR1 mRNA ISH no expression (score = 0). B, FGF2 mRNA ISH expression (score = 2). C, FGF9 mRNA ISH expression (score = 2). FGF, fibroblast growth factor; FGFR, fibroblast growth factor receptor; mRNA, messenger RNA; ISH, in situ hybridization.
