Table 4.
Coefficients for determining the rupture threshold of a resonant sized UCA via (5). ‘1 cycle’ and ‘Steady State’ refers to single cycle and steady state acoustic excitations, respectively. The goodness-of-fit parameters coefficient of determination r2 and standard error σX̄ are also shown.
| UCA | Fluid | Deviations from ambient pressure (mmHg) |
Acoustic excitation |
a1 | a2 | r2 | σX̄ (MPa) |
|---|---|---|---|---|---|---|---|
| Definity | Water | 0 | 1 cycle | 1.56 | 6.98 × 10−3 | 0.993 | 3.10 × 10−3 |
| Definity | Water | 0 | Steady state | 0.708 | 3.60 × 10−2 | 0.994 | 3.40 × 10−3 |
| Definity | Blood | 0 | 1 cycle | 1.46 | 8.02 × 10−3 | 0.993 | 3.00 × 10−3 |
| Definity | Blood | 0 | Steady state | 1.03 | 2.00 × 10−2 | 0.992 | 4.00 × 10−3 |
| Definity | Blood | 95 | 1 cycle | 1.49 | 7.55 × 10−3 | 0.991 | 3.00 × 10−3 |
| Definity | Blood | 95 | Steady state | 0.994 | 2.17 × 10−2 | 0.992 | 4.00 × 10−3 |
| Definity | Blood | 130 | 1 cycle | 1.50 | 7.44 × 10−3 | 0.991 | 3.40 × 10−3 |
| Definity | Blood | 130 | Steady state | 0.991 | 2.19 × 10−2 | 0.992 | 3.90 × 10−3 |
| Optison | Blood | 0 | 1 cycle | 1.33 | 5.95 × 10−3 | 0.997 | 1.40 × 10−3 |
| Optison | Blood | 0 | Steady state | 1.17 | 9.03 × 10−3 | 0.994 | 2.10 × 10−3 |
| Sonazoid | Blood | 0 | 1 cycle | 1.16 | 1.66 × 10−2 | 0.993 | 3.60 × 10−3 |
| Sonazoid | Blood | 0 | Steady state | 1.03 | 2.16 × 10−2 | 0.997 | 2.30 × 10−3 |