Table 2.
Clinical and biochemical parameters of the study population according to waist circumference
| Parameters | WC ≤ 102 cm (n. 52) | WC > 102 cm (n. 24) | p values |
|---|---|---|---|
| Age (years) | 53.6 ± 6.0 | 53.4 ± 5.2 | 0.900 |
| BMI (kg/m2) | 24.0 ± 2.5 | 29.1 ± 2.5 | <0.0001 |
| SBP (mmHg) | 122.5 (90–160) | 120.0 (100–160) | 0.819 |
| DBP (mmHg) | 80.0 (65–95) | 80.0 (60–100) | 0.305 |
| FPG (mg/dl) | 101.4 ± 12 | 99.9 ± 11.7 | 0.613 |
| Insulin (mU/l) | 3.6 (1.2–26.4) | 10.4 (3.3–28.7) | 0.0006 |
| HoMA-IR | 0.9 (0.4–7.7) | 2.7 (0.7–8.4) | 0.0016 |
| Total cholesterol (mg/dl) | 212.0 ± 50.1 | 199.5 ± 35.2 | 0.273 |
| HDL (mg/dl) | 52.7 ± 11.8 | 43.6 ± 9.1 | 0.001 |
| LDL (mg/dl) | 132.9 ± 46.5 | 123.0 ± 30.2 | 0.344 |
| TG (mg/dl) | 149.8 ± 81.5 | 165.0 ± 53.4 | 0.407 |
| BPA (ng/ml) | 0.86 ± 0.72 | 1.44 ± 0.74 | 0.002 |
| IL-6 (pg/ml) | 0.77 (0.06–2.2) | 0.78 (0.07–3.43) | 0.030 |
| MCP-1 (pg/ml) | 26.9 ± 25.4 | 28.3 ± 19.3 | 0.808 |
| TNFα (pg/ml) | 1.1 (0.5–9.1) | 3.2 (0.6–8.3) | 0.007 |
Data are expressed as mean ± standard deviation or median, according to variable distribution. In particular, SBP, DBP, Insulin, HoMA-IR, IL-6 and TNFα were expressed as median with range. Differences in variables between groups were analyzed using the unpaired Student t test or Mann-Whitney U test, when appropriate.
BMI body mass index, WC waist circumference, SBP systolic blood pressure, DBP diastolic blood pressure, FPG fasting plasma glucose, HoMA-IR homeostasis model of assessment-insulin resistance, HDL high-density lipoprotein, LDL low-density lipoprotein, TG triglycerides, BPA bisphenol-A, IL-6 interleukin-6, MCP-1 monocyte chemoattractant protein-1, TNFα tumor necrosis factor-alpha.