Table 3.
Adverse events (CTCAE version 3.0)
| Adverse event | Grade ½, n (%) | Grade 3, n (%) | Grade 4, n (%) |
|---|---|---|---|
| Anemia | 1 (6.3) | 0 (0) | 0 (0) |
| Elevation of AST | 2 (12.5) | 1 (6.3) | 0 (0) |
| Elevation of ALT | 2 (12.5) | 1 (6.3) | 0 (0) |
| Elevation of creatinine | 1 (6.3) | 0 (0) | 0 (0) |
| Albuminuria | 1 (6.3) | 0 (0) | 0 (0) |
| Interstitial lung disease | 0 (0) | 1 (6.3) | 0 (0) |
| Acneiform eruption | 5 (31.3) | 0 (0) | 0 (0) |
| Rash | 4 (25.0) | 0 (0) | 0 (0) |
| Dry skin | 1 (6.3) | 0 (0) | 0 (0) |
| Paronychia | 1 (6.3) | 0 (0) | 0 (0) |
| Stomatitis | 3 (18.8) | 0 (0) | 0 (0) |
| Glossitis | 1 (6.3) | 0 (0) | 0 (0) |
| Diarrhea | 2 (12.5) | 0 (0) | 0 (0) |
| Anorexia | 2 (12.5) | 0 (0) | 0 (0) |
| Malaise | 1 (6.3) | 0 (0) | 0 (0) |
| Hypotension | 1 (6.3) | 0 (0) | 0 (0) |
| Dysgeusia | 1 (6.3) | 0 (0) | 0 (0) |
CTCAE Common Terminology Criteria for Adverse Event, AST aspartate aminotransferase, ALT alanine aminotransferase.