Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Jun 4;13:180. doi: 10.1186/s12967-015-0535-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Verma et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Blood NK cell cytotoxicity (apoptosis and necrosis of K562 cells—see “Patients and methods” for further details) elicited by BMCs from women with LLABCs, prior to NAC, and HFDs. Differential cytotoxicity documented depending on the subsequent pathological response elicited in the breast cancers after NAC. [Groups I and II (good responders): 37.8 ± 8.50%; Groups III and IV (poor responders): 22.8 ± 7.97%; HFDs 69.7 ± 10.0%]. There is a significant and graduated reduction of NK cell cytotoxicity in the different groups of responders to NAC (Groups I and II versus Groups III and IV [p = 0.017]). The most substantial reduction, compared with HFDs, was seen in poor responders (Groups III and IV) (p = 0.001). Spontaneous cytotoxicity in the assays was ≤4%. SPSS (version 19.0) used for data analysis and calculation of independent sample t tests for statistical significance.