. 2015 Jun 4;13:180. doi: 10.1186/s12967-015-0535-8

Table 3.

NK (CD3⁻CD16⁺CD56^dim) cells expressing granzyme B/perforin (cytotoxic activity) and NKG2D (activation) in the circulation of women with LLABCs and HFDS

Cell phenotypes and functional status	% in the circulation of women with LLABCs (n = 25)	% In the circulation of HFDs (n = 10)	P value
NK granzyme B⁺/perforin⁺	43.41 ± 4.00	60.26 ± 7.00	0.003*
NK-NKG2D⁺	8.32 ± 3.50	4.00 ± 1.50	0.078

LLABCs large (≥3 cm) and locally advanced breast cancers (T3–4 N1–2 M0), HFDs healthy female donors.

* Values significantly reduced.