Table 7.
Groups | Pre NAC intratumoural median (range)a | P valueb (GPR versus PPR, PCR versus non PCR) | Pre NAC peritumoural median (range)a | P valueb (GPR versus PPR, PCR versus non PCR) | Post NAC peritumoural median (range)a | P valuec (pre NAC versus post NAC) |
---|---|---|---|---|---|---|
Good pathological response (GPR, n = 9) | 5 (0–17) | 0.091 | 2 (0–17) | 0.042* | 1 (0–3) | 0.121 |
Poor pathological response (PPR, n = 7) | 1 (0–7) | 0 (0–5) | 1 (0–3) | 0.655 | ||
Pathological complete response (PCR, n = 6) | 4 (1–17) | 0.181 | 3 (2–17) | 0.005* | 2 (0–3) | 0.144 |
Non pathological complete response (non PCR, n = 10) | 1 (0–7) | 0.5 (0–5) | 1 (0–3) | 0.680 |
LLABCs large (≥3 cm) and locally advanced breast cancers (T3–4 N1–2 M0), NAC neoadjuvant chemotherapy.
* Statistically significant.
aTotal cell count per 5 HPFs (core biopsies of breast cancers).
bMann–Whitney U test.
cWilcoxon signed rank test.