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. 2015 Jun 4;13:180. doi: 10.1186/s12967-015-0535-8

Table 7.

Analyses of tumour-infiltrating CD56+ cells in LLABCs pre and post NAC

Groups Pre NAC intratumoural median (range)a P valueb (GPR versus PPR, PCR versus non PCR) Pre NAC peritumoural median (range)a P valueb (GPR versus PPR, PCR versus non PCR) Post NAC peritumoural median (range)a P valuec (pre NAC versus post NAC)
Good pathological response (GPR, n = 9) 5 (0–17) 0.091 2 (0–17) 0.042* 1 (0–3) 0.121
Poor pathological response (PPR, n = 7) 1 (0–7) 0 (0–5) 1 (0–3) 0.655
Pathological complete response (PCR, n = 6) 4 (1–17) 0.181 3 (2–17) 0.005* 2 (0–3) 0.144
Non pathological complete response (non PCR, n = 10) 1 (0–7) 0.5 (0–5) 1 (0–3) 0.680

LLABCs large (≥3 cm) and locally advanced breast cancers (T3–4 N1–2 M0), NAC neoadjuvant chemotherapy.

* Statistically significant.

aTotal cell count per 5 HPFs (core biopsies of breast cancers).

bMann–Whitney U test.

cWilcoxon signed rank test.