Table S4.
Multivariate analysis of breast cancer-specific survival after stratification by age
| Variable | <50 years old
|
<50 years old
|
||
|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | |
| Year of diagnosis | ||||
| 1998–2002 | Reference | Reference | ||
| 2003–2007 | 0.51 (0.17–1.50) | 0.220 | 0.64 (0.38–1.09) | 0.100 |
| Race | ||||
| Black | Reference | Reference | ||
| White | 0.39 (0.12–1.29) | 0.122 | 0.53 (0.32–0.88) | 0.014 |
| Other* | 1.45 (0.37–5.73) | 0.599 | 0.25 (0.07–0.83) | 0.024 |
| Marital status | ||||
| Non-married† | Reference | Reference | ||
| Married | 0.59 (0.24–1.48) | 0.265 | 0.50 (0.33–0.75) | 0.001 |
| Poverty–high school index | ||||
| Low SEP | Reference | Reference | ||
| Middle SEP | 1.35 (0.46–4.00) | 0.586 | 1.36 (0.82–2.26) | 0.235 |
| High SEP | 0.73 (0.19–2.78) | 0.641 | 0.55 (0.27–1.09) | 0.087 |
| Laterality | ||||
| Left | Reference | Reference | ||
| Right | 0.44 (0.17–1.15) | 0.093 | 0.72 (0.48–1.08) | 0.110 |
| Primary site | ||||
| Single-quadrant lesions | Reference | Reference | ||
| Multi-quadrant lesions | 0.66 (0.15–2.89) | 0.576 | 1.16 (0.65–2.05) | 0.617 |
| ER status | ||||
| Negative | Reference | Reference | ||
| Positive | 0.97 (0.26–3.65) | 0.963 | 0.99 (0.53–1.86) | 0.973 |
| PR status | ||||
| Negative | Reference | Reference | ||
| Positive | 0.43 (0.13–1.39) | 0.158 | 0.75 (0.44–1.29) | 0.299 |
| Grade | ||||
| I | Reference | Reference | ||
| II | 2.83 (0.36–22.50) | 0.325 | 1.72 (0.83–3.54) | 0.144 |
| III and IV | 2.42 (0.30–19.71) | 0.408 | 1.67 (0.79–3.48) | 0.179 |
| RT | ||||
| No | Reference | Reference | ||
| Yes | 0.37 (0.15–0.91) | 0.030 | 0.80 (0.52–1.21) | 0.285 |
Notes:
*
Including American Indian/Alaskan Native and Asian/Pacific Islander.
†
Including divorced, widowed, single (never married), and separated.
Abbreviations: ER, estrogen receptor; PR, progesterone receptor; HR, hazard ratio; CI, confidence interval; SEP, socioeconomic position; RT, radiotherapy.