Table S3.
Multivariate analysis of overall survival after stratification by age
| Variable | <50 years old
|
>50 years old
|
||
|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | |
| Year of diagnosis | ||||
| 1998–2002 | Reference | Reference | ||
| 2003–2007 | 0.69 (0.41–1.16) | 0.162 | 0.84 (0.71–1.00) | 0.050 |
| Race | ||||
| Black | Reference | Reference | ||
| White | 0.61 (0.34–1.10) | 0.099 | 0.77 (0.64–0.92) | 0.004 |
| Other* | 0.77 (0.35–1.68) | 0.512 | 0.56 (0.41–0.77) | <0.001 |
| Marital status | ||||
| Non-married† | Reference | Reference | ||
| Married | 0.77 (0.50–1.17) | 0.217 | 0.54 (0.47–0.61) | <0.001 |
| Poverty–high school index | ||||
| Low SEP | Reference | Reference | ||
| Middle SEP | 0.94 (0.58–1.53) | 0.802 | 1.17 (1.00–1.38) | 0.055 |
| High SEP | 0.62 (0.34–1.11) | 0.106 | 0.96 (0.80–1.15) | 0.651 |
| Laterality | ||||
| Left | Reference | Reference | ||
| Right | 0.82 (0.54–1.22) | 0.325 | 1.04 (0.92–1.18) | 0.516 |
| Primary site | ||||
| Single-quadrant lesions | Reference | Reference | ||
| Multi-quadrant lesions | 0.84 (0.44–1.57) | 0.576 | 1.25 (1.06–1.49) | 0.010 |
| ER status | ||||
| Negative | Reference | Reference | ||
| Positive | 1.03 (0.54–1.97) | 0.928 | 1.08 (0.87–1.33) | 0.492 |
| PR status | ||||
| Negative | Reference | Reference | ||
| Positive | 0.56 (0.32–0.97) | 0.038 | 0.88 (0.74–1.04) | 0.129 |
| Grade | ||||
| I | Reference | Reference | ||
| II | 0.80 (0.41–1.55) | 0.502 | 1.01 (0.84–1.21) | 0.912 |
| III and IV | 1.04 (0.54–1.99) | 0.916 | 0.98 (0.81–1.18) | 0.794 |
| RT | ||||
| No | Reference | Reference | ||
| Yes | 0.47 (0.31–0.72) | <0.001 | 0.61 (0.54–0.69) | <0.001 |
Notes:
*
Including American Indian/Alaskan Native and Asian/Pacific Islander.
†
Including divorced, widowed, single (never marcried), and separated.
Abbreviations: HR, hazard ratio; CI, confidence interval; SEP, socioeconomic position; ER, estrogen receptor; PR, progesterone receptor; RT, radiotherapy.