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. 2015 Jun 16;16:34. doi: 10.1186/s12868-015-0171-5

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© Dickson et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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CCG-17444 enhances neurite outgrowth in CGNs and counteracts the inhibitory action of Nogo66. Postnatal d8 CGNs were treated for 24 h with CCG-17444, vehicle control, or the ROCK inhibitor Y27632 (positive control). a Nogo66 inhibits neurite outgrowth in CGNs, and CCG-17444 counteracts this inhibition. Scale bar 100 μm. b Quantitation of neurite length. Data are mean ± SD (n = 3, *p < 0.0001, Student’s t test).