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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Biomaterials. 2015 May 15;59:30–38. doi: 10.1016/j.biomaterials.2015.04.040

Fig. 7.

Fig. 7

Schematic illustration of differences in distribution and concentration of circulating biomarkers in laser-treated and non-treated skins. (A) The skin without laser treatment. (B) Strong capture of circulating biomarkers occurs only on a MN that is physically close to a damaged capillary vessel like MN#1, but not on a MN that is away from an injured vessel like MN#3 in the absence of laser treatment. (C) In contrast, all MNs on the array are exposed to uniformly high concentrations of circulating biomarkers in laser-treated skin owing to laser-induced extravasation.