. Author manuscript; available in PMC: 2015 Jun 15.

Published in final edited form as: Ann Hematol. 2014 Feb 28;93(7):1139–1148. doi: 10.1007/s00277-014-2037-9

Table 5.

Transfusions effect on biomarkers in thalassemia patients

Marker/finding	Transfused (n=51)^*	Non-transfused (n=25)	p value
TRV	2.3 (0.3)	2.7 (0.6)	0.0006
EF	0.68 (0.06)	0.72 (0.06)	0.004
TAT	3.5 (2.7)	6.5(12)	ns
Platelet count	433 (230)	501 (180)	ns
P-selectin	34 (12)	31 (10)	ns
sCD40L	2.1 (1.6)	4.0 (5.1)	0.05
Free Hb (PFH)	75 (33)	95 (42)	0.03
NOx	8.3 (11)	4.8 (2.7)	ns
LDH	329 (249)	517 (234)	0.002
Bilirubin	2.2 (1.4)	2.5 (1.4)	ns
BNP	28 (35)	30 (36)	ns
ET-1	43 (36)	66 (42)	0.02
Ferritin	2447 (2680)	847(1280)	0.01

Regularly transfused patients consists of TM (n=41) and patients with TI and H-CS (n=10) transitioned to frequent or regular t transfusions (≥ 8times/year). TAT, thrombin-anti thrombin. BNP, brain natriuretic protein. ET-1, endothelin-1.

ns, not significant.