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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: J Mol Cell Cardiol. 2015 Apr 25;84:104–111. doi: 10.1016/j.yjmcc.2015.04.017

Figure 2.

Figure 2

PLM enhances voltage-dependent inactivation of ICa. ICa was measured in freshly isolated myocytes from WT and KO hearts, using Ba2+ (2 mM) as permeant ion. A. Voltage-clamp protocol: test pulses from −90 to +50 mV (in 10 mV increments) were extended from 60 to 300 ms duration (for simplicity, only one test pulse is shown). B. Representative IBa traces at −10 mV from WT and KO myocytes are shown. Note prolonged time course of IBa in KO compared to WT myocyte. C. I-V curves from WT (○; n=5) and KO myocytes (●; n=5).