. Author manuscript; available in PMC: 2016 Jul 1.

Published in final edited form as: Brain Behav Immun. 2014 Dec 20;47:58–65. doi: 10.1016/j.bbi.2014.11.018

Table 4.

Significant adjusted associations between cytokine genotype and sleep onset latency group (n=285)

Gene	SNP	Model	OR	95% CI	p	Full models
ILIB	rs1143642	D	2.37	1.21, 4.64	.012	χ²=16.5, p=.021
ILIB	rs1143623	A	0.54	0.31, 0.95	.034	χ²=15.2, p=.034
IL6	rs4719714	A	1.71	1.03, 2.85	.039	χ²=14.5, p=.044
IL13	rs1295686	A	0.59	0.36, 0.97	.037	χ²=14.8, p=.039
NFKB1	rs4648110	R	4.28	1.76, 10.44	.001	χ²=20.0, p=.006
TNFA	rs2857602	R	2.57	1.09, 6.06	.030	χ²=14.7, p=.040

Notes. Models predict membership in the group with sleep onset latency >30 minutes, and the group with sleep onset latency ≤30 minutes serves as the reference. All models adjusted for genomic estimates of ancestry, self-reported race/ethnicity, and viral load. The sample size for adjusted analyses was 285 due to missing viral load values for 22 participants. A = additive model; CI = confidence interval; D = dominant model; IL = interleukin; NKFKB = nuclear factor of kappa light polypeptide gene enhancer in B cells; OR = odds ratio based on dose of minor allele; R = recessive model; TNFA = tumor necrosis factor alpha.