Table 3. Results of the subgroup analysis by study population.
Study population | SNPs | Inheritance Model | OR | 95% CI | P | P(Q test)* |
---|---|---|---|---|---|---|
Chinese | ||||||
rs12423791 | ||||||
C vs. G | 1.24 | 1.04–1.48 | 0.02 | 0.19 | ||
CC vs. GG | 1.39 | 1.00–1.93 | 0.05 | 0.48 | ||
CG vs. GG | 1.37 | 1.12–1.68 | 0.002 | 0.48 | ||
CC+CG vs. GG | 1.40 | 1.16–1.69 | <.001 | 0.45 | ||
CC vs. CG+GG | 1.17 | 0.91–1.50 | 0.21 | 0.56 | ||
rs6241 | ||||||
A vs. G | 1.05 | 0.92–1.19 | 0.50 | 0.30 | ||
AA vs. GG | 1.10 | 0.87–1.40 | 0.43 | 0.37 | ||
AG vs. GG | 1.05 | 0.85–1.29 | 0.68 | 0.99 | ||
AA+AG vs. GG | 1.06 | 0.87–1.30 | 0.54 | 0.80 | ||
AA vs. AG+GG | 1.07 | 0.88–1.30 | 0.48 | 0.24 | ||
Japanese | ||||||
rs12423791 | ||||||
C vs. G | 0.92 | 0.78–1.09 | 0.33 | 0.15 | ||
CC vs. GG | 0.97 | 0.75–1.26 | 0.83 | 0.20 | ||
CG vs. GG | 0.91 | 0.79–1.04 | 0.17 | 0.71 | ||
CC+CG vs. GG | 0.89 | 0.76–1.05 | 0.18 | 0.25 | ||
CC vs. CG+GG | 1.00 | 0.78–1.29 | 0.99 | 0.15 | ||
rs6241 | ||||||
A vs. G | 0.99 | 0.90–1.10 | 0.91 | 0.29 | ||
AA vs. GG | 1.01 | 0.83–1.22 | 0.96 | 0.33 | ||
AG vs. GG | 1.03 | 0.86–1.24 | 0.73 | 0.56 | ||
AA+AG vs. GG | 1.02 | 0.86–1.21 | 0.79 | 0.41 | ||
AA vs. AG+GG | 0.98 | 0.84–1.13 | 0.74 | 0.41 |
*The Q statistic was used to estimate heterogeneity, and a P≤0.10 was considered statistically significant for the Q-statistic test.