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. 2015 Jun 15;10(6):e0130052. doi: 10.1371/journal.pone.0130052

Fig 6. Fibrosis-related markers were significantly upregulated in AAV-HBV injected mice.

Fig 6

(a, b) ELISA measurements of the collagen I (a) and III (b) levels in serum and liver samples. (c) ELISA measurements of the TGF-β1 and TIMP-1 protein levels in the serum. (d) Reverse transcription quantitative PCR measurements of Tgf-β1 and Timp-1 mRNA levels in the liver. Statistical analyses were performed using a two-way analysis of variance. Data represent the mean±SD (n = 4). HBV(-) mice, PBS injected mice.