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. 2015 Jun 15;10(6):e0130551. doi: 10.1371/journal.pone.0130551

Fig 3. Down-regulated HOXB7 decreased cell proliferation in vivo and its effect on cell cycle distribution.

Fig 3

(A) Tumors generated by injection of EC109/KYSE150 with stable knockdown HOXB7 protein and control cells. (B) The weight and volume of tumors from the HOXB7-knockdown cells were relatively lower than those from the control cells. (C) Representative histograms analyzed by flow cytometry showed the cell cycle profiles of the ESCC cells. In the cells with stable knockdown HOXB7 protein, the cell number at S and G2 phases decreased compared with the control cells. (D) Proportion of cells in different phases of the cell cycle. Error bars represent mean±SD from 3 independent experiments. *, P<0.05.