Table 2. Lead Fixation Method and Lead Insulation vs. Early Heart Perforation Under Logistic Regression Analysis.

	Number of Event––no. (%)			Adjusted Odds Ratio and 95% CI
	Active	Passive	Both	Active vs. Both		Passive vs. Both		Active vs. Passive
Outcome	(n = 3,766)	(n = 29,250)	(n = 3,088)	OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P
Early heart perforation	3 (0.08)	17 (0.06)	2 (0.06)	1.16 (0.19–7.23)	0.870	0.66 (0.11–3.93)	0.647	1.77 (0.41–7.54)	0.441
	Silicone	Polyurethane	Both Insulation	Silicone vs. Both Insulation		Polyurethane vs. Both Insulation		Silicone vs. Polyurethane
Outcome	(n = 29,453)	(n = 3,140)	(n = 3,511)	OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P
Early heart perforation	16 (0.05)	2 (0.06)	4 (0.11)	0.54 (0.18–1.64)	0.275	0.47 (0.08–2.60)	0.384	1.15 (0.26–5.10)	0.850

The odds ratios (OR) were adjusted for all covariates listed in Table 1.