Table 1. Clinicopathological characteristics of the 77 HCC patients with PVTT/HVTT.
| Group 1 (n = 38) | Group 2 (n = 39) | p value | |
|---|---|---|---|
| Age (years) | 49.3±1.5 | 47.9±2.2 | 0.609 |
| Gender | 0.571 | ||
| Male | 37 (97.4%) | 37 (94.9%) | |
| Female | 1 (2.6%) | 2 (5.1%) | |
| HBsAg status | 0.556 | ||
| Negative | 2 (5.3%) | 1 (2.6%) | |
| Positive | 35 (92.1%) | 36 (92.3%) | |
| Unknown | 1 (2.6%) | 2 (5.1%) | |
| Preoperative HBV-DNA | 0.662 | ||
| <1×103 | 10 (26.3%) | 12 (30.8%) | |
| ≥1×103 | 20 (52.6%) | 19 (48.7%) | |
| Unknown | 8 (21.1%) | 8 (20.5%) | |
| Preoperative AFP level | 0.935 | ||
| ≤400 ng/ml | 13 (34.2%) | 13 (33.3%) | |
| >400 ng/ml | 25 (65.8%) | 26 (66.7%) | |
| Preoperative ALT level (U/L) | 43(10~713) | 40.5(14~208) | 0.433 |
| Preoperative Hgb level (g/L) | 148.54±3.27 | 145.74±3.08 | 0.534 |
| Preoperative PLT level (109/L) | 197.7±16.7 | 183.4±11.0 | 0.472 |
| Preoperative Child-Pugh score | 0.651 | ||
| Child A (5) | 11 (28.9%) | 15 (38.5%) | |
| Child A (6) | 18 (47.4%) | 17 (43.6%) | |
| Child B (7) | 5 (13.2%) | 3 (7.7%) | |
| Child B (8) | 2 (5.3%) | 1 (2.6%) | |
| Child B (9) | 1 (2.6%) | 0 (0.0%) | |
| Unknown | 1 (2.6%) | 3 (7.7%) | |
| Preoperative ICGR15 (%) | 5.58±0.96 | 4.46±0.68 | 0.342 |
| Number of tumors | 0.424 | ||
| Solitary | 21 (55.3%) | 18 (46.2%) | |
| Multiple | 17 (44.7%) | 21 (53.8%) | |
| Maximum diameter of tumor (cm) | 9.91±0.71 | 10.08±0.71 | 0.866 |
| Uni/Bilobular disease | 0.249 | ||
| Unilobular disease | 36 (94.7%) | 34 (87.2%) | |
| Bilobular disease | 2 (5.3%) | 5 (12.8%) | |
| Adjacent organ invasion | 0.883 | ||
| Negative | 24 (63.2%) | 24 (61.5%) | |
| Positive | 14 (36.8%) | 15 (38.5%) | |
| Operative procedure | 0.289 | ||
| Minor | 24 (63.2%) | 29 (74.4%) | |
| Major | 14 (36.8%) | 10 (25.6) | |
| Total occlusion time of the hepatic inflow (min) | 15.95±2.11 | 20.64±1.86 | 0.098 |
| Total operative time (min) | 176.2±11.2 | 186.4±9.8 | 0.492 |
| Blood loss (ml) | 350 (100~4300) | 600 (100~2000) | 0.002 |
| Blood transfusion (ml) | 0±2300 | 200±1700 | 0.002 |
| Surgical margin | 1.000 | ||
| ≤1 cm | 28 (73.7%) | 28 (71.8%) | |
| >1 cm | 9 (23.7%) | 9 (23.1%) | |
| Unknown | 1 (2.6%) | 2 (5.1%) | |
| Histologic grade of tumor cells a | 0.527 | ||
| I-II | 12 (31.6%) | 15 (38.5%) | |
| III-IV | 26 (68.4%) | 24 (61.5%) | |
| Postoperative complication | 0.817 | ||
| Negative | 31 (81.6%) | 31 (79.5%) | |
| Positive | 7 (18.4%) | 8 (20.5%) | |
| Postoperative hospital stay (days) | 11(8~28) | 11(8~83) | 0.762 |
HBsAg: surface antigen of the hepatitis B virus; ALT: alanine transaminase; Hgb: hemoglobin; PLT: platelet; ICGR15: indocyanine green retention rate at 15 min
aHistologic grade of HCC was assessed according to the Edmondson-Steiner grade system [45].