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. 2015 Jun 15;10(6):e0130382. doi: 10.1371/journal.pone.0130382

Table 2. Representative gene ontology (GO) terms associated with actin cytoskeleton organization based on the differentially expressed genes (DEGs, fold changes > 2) between IVP and IVO blastocysts.

Annotation Cluster 1 Enrichment Score: 4.54 Count P_Value Benjamini
    GOTERM_CC_FAT extracellular region 203 0.000091 0.021
Annotation Cluster 2 Enrichment Score: 4.38 Count P_Value Benjamini
    GOTERM_BP_FAT chemical homeostasis 65 3.8E-07 0.0012
    GOTERM_BP_FAT ion homeostasis 54 0.0000014 0.0023
    GOTERM_BP_FAT homeostatic process 89 0.0000026 0.0028
    GOTERM_BP_FAT cation homeostasis 38 0.0000046 0.0036
    GOTERM_BP_FAT cellular chemical homeostasis 49 0.0000058 0.0037
    GOTERM_BP_FAT cellular ion homeostasis 48 0.0000063 0.0033
    GOTERM_BP_FAT cellular cation homeostasis 32 0.00002 0.0078
    GOTERM_BP_FAT cellular homeostasis 56 0.000036 0.013
    GOTERM_BP_FAT di-, tri-valent inorganic cation homeostasis 30 0.00006 0.017
    GOTERM_BP_FAT cellular di-, tri-valent inorganic cation homeostasis 28 0.000083 0.022
    GOTERM_BP_FAT metal ion homeostasis 23 0.00023 0.039
    GOTERM_BP_FAT cellular metal ion homeostasis 22 0.00027 0.04
    GOTERM_BP_FAT calcium ion homeostasis 20 0.00098 0.11
    GOTERM_BP_FAT cellular calcium ion homeostasis 19 0.0015 0.13
    GOTERM_BP_FAT regulation of membrane potential 19 0.025 0.5
Annotation Cluster 3 Enrichment Score: 3.5 Count P_Value Benjamini
    GOTERM_CC_FAT sarcomere 20 0.00012 0.019
    GOTERM_CC_FAT Z disc 14 0.00023 0.021
    GOTERM_CC_FAT I band 15 0.00029 0.019
    GOTERM_CC_FAT contractile fiber part 20 0.00034 0.02
    GOTERM_CC_FAT contractile fiber 21 0.00047 0.022
    GOTERM_CC_FAT myofibril 20 0.00072 0.027
Annotation Cluster 4 Enrichment Score: 3.39 Count P_Value Benjamini
    GOTERM_MF_FAT actin binding 47 0.00043 0.087
    GOTERM_MF_FAT cytoskeletal protein binding 62 0.00052 0.087
Annotation Cluster 5 Enrichment Score: 2.75 Count P_Value Benjamini
    GOTERM_CC_FAT extracellular matrix 48 0.00068 0.028
    GOTERM_CC_FAT proteinaceous extracellular matrix 46 0.00095 0.034
    GOTERM_CC_FAT extracellular region part 95 0.0058 0.14
Annotation Cluster 6 Enrichment Score: 2.72 Count P_Value Benjamini
    GOTERM_MF_FAT ion binding 456 0.0000011 0.00056
    GOTERM_MF_FAT cation binding 448 0.0000027 0.00095
    GOTERM_MF_FAT metal ion binding 442 0.0000056 0.0015
    GOTERM_MF_FAT transition metal ion binding 275 0.058 0.72
    GOTERM_MF_FAT zinc ion binding 222 0.085 0.78