. 2015 Jun 15;10(6):e0129621. doi: 10.1371/journal.pone.0129621

Table 2. Parameters of DCE-MRI in different groups.

	No fibrosis group (F0, n = 13)	Mild fibrosis group (F1-F2, n = 11)	Advanced fibrosis group (F3-F4, n = 11)	F value	P value
Ktrans(min-1)	0.078±0.017	0.088±0.013	0.104±0.017^** ^#	7.991	0.002
Kep(min-1)	0.273±0.060	0.309±0.055	0.297±0.051	1.271	0.294
Ve	0.300±0.085	0.295±0.057	0.362±0.073^* ^#	2.863	0.072
iAUC	5.205±1.692	6.694±1.583	8.701±2.069^** ^#	11.409	0.000

Note.—Data are mean ± standard deviations.

*P<0.05,

**P<0.01 for comparison with rats in normal group.

^# P<0.05 for comparison with rats in mild group.

K^trans = transfer constant, K_ep = rate constant, V_e = extravascular extracellular volume fraction; iAUC = initial area under the gadolinium concentration-time curve.