Table 5. Variables at baseline independently correlated to poor adherence to guidelines (VKA start <7 days for patients without cancer, and LMWH alone for patients with cancer).
Patients without cancer | p | Patients with cancer | p | ||
---|---|---|---|---|---|
Patient characteristics | OR (95% CI) | OR (95% CI) | |||
Gender (males) | 0.89 (0.84–0.95) | <0.001 | - | - | |
Age >70 years | - | - | 1.39 (1.24–1.56) | <0.001 | |
Chronic heart disease | - | - | 1.50 (1.15–1.95) | 0.003 | |
Chronic lung disease | - | - | 1.36 (1.14–1.63) | 0.001 | |
Recent major bleeding | 2.72 (2.28–3.24) | <0.001 | - | - | |
Anemia | 1.72 (1.62–1.83) | <0.001 | 0.55 (0.49–0.62) | <0.001 | |
Postoperative | 1.20 (1.09–1.32) | <0.001 | - | - | |
Immobility ≥4 days | 1.98 (1.86–2.10) | <0.001 | 0.67 (0.58–0.78) | <0.001 | |
Prior VTE | 0.87 (0.80–0.94) | 0.001 | - | - | |
Pulmonary embolism (vs. DVT) | 0.59 (0.56–0.63) | <0.001 | 1.15 (1.03–1.28) | 0.015 | |
CrCl levels >60 mL/min | 1 (ref.) | - | - | ||
CrCl levels 30–60 mL/min | 1.40 (1.30–1.52) | <0.001 | - | - | |
CrCl levels <30 mL/min | 2.31 (2.06–2.59) | <0.001 | - | - | |
Chronic liver disease | 1.82 (1.30–2.55) | 0.001 | - | - | |
Inflammatory bowel disease | 2.06 (1.44–2.94) | <0.001 | - | - | |
Mental disturbances | 2.82 (2.48–3.21) | <0.001 | - | - |
Abbreviations: OR, odds ratio; CI, confidence intervals; CrCl, creatinine clearance; VTE, venous thromboembolism; DVT, deep vein thrombosis.