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. 2015 Jun 15;10(6):e0128741. doi: 10.1371/journal.pone.0128741

Table 5. Variables at baseline independently correlated to poor adherence to guidelines (VKA start <7 days for patients without cancer, and LMWH alone for patients with cancer).

Patients without cancer p Patients with cancer p
Patient characteristics OR (95% CI) OR (95% CI)
Gender (males) 0.89 (0.84–0.95) <0.001 - -
Age >70 years - - 1.39 (1.24–1.56) <0.001
Chronic heart disease - - 1.50 (1.15–1.95) 0.003
Chronic lung disease - - 1.36 (1.14–1.63) 0.001
Recent major bleeding 2.72 (2.28–3.24) <0.001 - -
Anemia 1.72 (1.62–1.83) <0.001 0.55 (0.49–0.62) <0.001
Postoperative 1.20 (1.09–1.32) <0.001 - -
Immobility ≥4 days 1.98 (1.86–2.10) <0.001 0.67 (0.58–0.78) <0.001
Prior VTE 0.87 (0.80–0.94) 0.001 - -
Pulmonary embolism (vs. DVT) 0.59 (0.56–0.63) <0.001 1.15 (1.03–1.28) 0.015
CrCl levels >60 mL/min 1 (ref.) - -
CrCl levels 30–60 mL/min 1.40 (1.30–1.52) <0.001 - -
CrCl levels <30 mL/min 2.31 (2.06–2.59) <0.001 - -
Chronic liver disease 1.82 (1.30–2.55) 0.001 - -
Inflammatory bowel disease 2.06 (1.44–2.94) <0.001 - -
Mental disturbances 2.82 (2.48–3.21) <0.001 - -

Abbreviations: OR, odds ratio; CI, confidence intervals; CrCl, creatinine clearance; VTE, venous thromboembolism; DVT, deep vein thrombosis.