Table 4. Sensitivity and specificity of N-glycan biomarkers for the diagnosis and differential diagnosis of LCMM.
| Cut off value | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Accuracy (%) |
|---|---|---|---|---|---|
| Peak3 (LCMM vs Healthy control) (5.205) | 88.1 | 92.9 | 92.5 | 88.6 | 90.5 |
| Peak7 (LCMM vs Healthy control) (4.105) | 92.9 | 97.6 | 97.5 | 93.2 | 95.2 |
| Peak3 (LCMM vs IgG MM) (6.855) | 100.0 | 76.2 | 80.8 | 100.0 | 88.1 |
| Peak7 (LCMM vs IgA MM) (4.220) | 92.9 | 82.9 | 84.8 | 91.9 | 88.0 |
Note: Abbreviations: PPV: positive predictive value; NPV: negative predictive value.