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. 2015 Jun 15;10(6):e0130166. doi: 10.1371/journal.pone.0130166

Fig 2. Systemic sclerosis (SSc) sera impair wound healing capacity of dermal microvascular endothelial cells (dMVECs).

Fig 2

Wound healing capacity of dMVECs was assayed in the presence of sera from healthy controls (CTR, n = 8) and SSc patients, treatment-naïve (n = 8) or under cyclophosphamide (CYC) treatment (n = 13). (A) Representative images of the wounded area at 0 hours and 24 hours after scratching. Original magnification, ×10. (B) Quantitative analysis of the percentage of wound repair. Data are means ± SEM of three independent experiments performed in duplicate with each one of the three dMVEC lines. **p<0.005 vs. healthy controls, §p<0.001 vs. naïve lSSc. dSSc, diffuse cutaneous SSc; lSSc, limited cutaneous SSc.