Table 1. Characteristics of pulmonary TB patients according to DM diagnosis, Mexico 2000–2012.
Characteristic | Total | Pulmonary TB with DM | Pulmonary TB without DM | p-value* |
---|---|---|---|---|
n = 181,378 | n = 34,988 (19.29%) | n = 146,390 (80.370%) | ||
Number/Total (%) | Number/Total (%) | Number/Total (%) | ||
Female | 66,189/181,377 (36.49) | 15,036/34,988 (42.97) | 51,153/146,389 (34.94) | <0.001 |
Age (years) [median (IQR)] | 46 (32–60) | 52 (44–61) | 43 (30–59) | <0.001** |
Region | ||||
Mexico City and Central region | 45,963/181,371 (25.34) | 9,214/34,987 (26.34) | 36,749 / 146,384 (25.34) | <0.001† |
Northern region | 62,756/181,371 (34.60) | 11,645/34,987 (33.38) | 51,111/ 146,384 (34.60) | <0.001† |
Southern region | 72,652/181,371 (40.06) | 14,128/34,987 (40.38) | 58,524/ 146,384 (39.98) | 0.169† |
Lack of access to social security | 51,646 /181,138 (28.51) | 13,303/34,957 (38.06) | 38,343/146,181 (26.23) | <0.001 |
Malnutrition | 18,484/ 181,378 (10.19) | 638/34,988 (1.82) | 17,846/146,390 (12.19) | <0.001 |
Cirrhosis | 351/181,378 (0.19) | 49/ 34,988 (0.14) | 302/146,390 (0.21) | 0.011 |
Treatment for a previous TB episode | 16,413 /178,780 (9.18) | 3,338/34,413 (9.70) | 13,075 /144,368 (9.06) | <0.001 |
Method for TB diagnosis | ||||
Culture | 1,935/181,092 (1.07) | 373/34,966 (1.07) | 1,562/146,126 (1.07) | 0.972† |
Sputum smear microscopy | 153,050/181,092 (84.52) | 30,962/34,966 (88.55) | 122,088/146,126 (83.55) | <0.001† |
Chest X rays | 17,820 /181,092 (9.84) | 2,365 /34,966 (6.76) | 15,455/146,126 (10.58) | <0.001† |
Histopathology | 1,054 /181,092 (0.58) | 155/34,966 (0.44) | 899/146,126 (0.62) | <0.001† |
Other | 7,233/181,092 (3.99) | 1,111/34,966 (3.18) | 6,122/146,126 (4.19) | <0.001† |
Antimicrobial susceptibility | ||||
Pansusceptible | 1,101/2,286 (48.16) | 243/672 (36.16) | 858/1,614 (53.16) | <0.001† |
Resistant | 1793/2,286 (8.44) | 67/672 (9.97) | 126/1,614 (7.81) | 0.090† |
MDR | 992/2,286 (43.39) | 362/672 (53.87) | 630/1,614 (39.03) | <0.001† |
Treatment outcome | ||||
Cure and treatment completion | 117,751/143,782 (81.90) | 25,623/29,534 (86.76) | 84,302/114,248 (80.54) | <0.001† |
Failure | 2,405/143,782 (1.67) | 621/29,534 (2.10) | 1,666/114,248 (1.59) | <0.001† |
Default | 11,188/143,782 (7.78) | 1,317/29,534 (4.46) | 9,043/114,248 (8.64) | <0.001† |
Death during treatment | 12,438/143,782 (8.65) | 1,973 /29,534 (6.68) | 10,465/114,248 (9.16) | <0.001† |
TB, Tuberculosis; DM, Diabetes mellitus; OR, Odds Ratio; CI, Confidence Interval; IQR, Interquartile range; MDR, multidrug resistance.
* Chi-square test.
** Mann–Whitney Test.
† Binomial test.