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. 2015 Jun 15;10(6):e0130405. doi: 10.1371/journal.pone.0130405

Table 3. Multivariate odds ratio for high blood pressure according to magnesium intake by obesity and menopause.

Variables Magnesium intake p for trend
Quartile 1 Quartile 2 Quartile 3 Quartile 4
Male
Obesity (≥25kg/m2)
No. of HBP subjects (%) 131 (36.4) 184 (45.0) 176 (41.6) 148 (40.0) -
Mg Intake range (mg/1000kcal) <102.6 102.6–137.0 137.0–174.0 ≥174.0 -
Model 1 a 1.00 1.43 (1.01–2.01) 1.22 (0.85–1.73) 1.05 (0.72–1.52) 0.1344
Model 2 b 1.00 1.36 (0.95–1.93) 1.29 (0.89–1.88) 1.06 (0.72–1.56) 0.2361
Model 3 c 1.00 1.42 (0.98–2.06) 1.40 (0.92–2.14) 1.20 (0.72–1.99) 0.2101
Normal weight (<25kg/m2)
No. of HBP subjects (%) 228 (23.0) 222 (25.3) 211 (24.0) 221 (24.3) -
Mg Intake range (mg/1000kcal) <105.4 105.4–135.5 135.6–170.6 ≥170.6 -
Model 1 a 1.00 1.09 (0.84–1.41) 1.01 (0.77–1.32) 0.91 (0.68–1.21) 0.6099
Model 2 b 1.00 1.14 (0.87–1.50) 1.06 (0.79–1.41) 0.96 (0.71–1.29) 0.6037
Model 3 c 1.00 1.14 (0.86–1.51) 1.06 (0.78–1.45) 0.93 (0.64–1.35) 0.5467
Female
Obesity (≥25kg/m2)
No. of HBP subjects (%) 150 (31.2) 127 (26.4) 108 (24.5) 82 (17.8) -
Mg Intake range (mg/1000kcal) <112.2 112.2–146.4 146.4–191.8 ≥191.8 -
Model 1 a 1.00 0.79 (0.56–1.13) 0.69 (0.47–1.00) 0.45 (0.32–0.64) <.0001
Model 2 b 1.00 0.81 (0.56–1.16) 0.70 (0.48–1.03) 0.46 (0.33–0.66) 0.0002
Model 3 c 1.00 0.76 (0.53–1.10) 0.64 (0.41–0.99) 0.40 (0.25–0.63) 0.0014
Normal weight (<25kg/m2)
No. of HBP subjects (%) 247 (13.7) 187 (11.3) 163 (10.4) 199 (13.8) -
Mg Intake range (mg/1000kcal) <110.6 110.6–141.6 141.6–181.9 ≥181.9 -
Model 1 a 1.00 0.87 (0.65–1.16) 0.83 (0.55–0.98) 0.94 (0.70–1.25) 0.1607
Model 2 b 1.00 0.85 (0.63–1.14) 0.72 (0.54–0.98) 0.93 (0.69–1.25) 0.1533
Model 3 c 1.00 0.88 (0.66–1.19) 0.77 (0.56–1.06) 1.02 (0.71–1.47) 0.1980
Menopause
Premenopause
No. of HBP subjects (%) 102 (9.5) 92 (8.0) 94 (7.9) 105 (8.9) -
Mg Intake range (mg/1000kcal) <110.6 110.6–140.6 140.6–181.1 ≥181.2 -
Model 1 a 1.00 0.73 (0.51–1.03) 0.68 (0.49–0.95) 0.69 (0.49–0.97) 0.0867
Model 2 b 1.00 0.70 (0.49–1.01) 0.70 (0.50–0.97) 0.69 (0.49–0.98) 0.1082
Model 3 c 1.00 0.70 (0.48–1.00) 0.70 (0.48–1.00) 0.67 (0.43–1.04) 0.1489
Postmenopause
No. of HBP subjects (%) 304 (37.5) 232 (32.0) 195 (29.9) 144 (25.9) -
Mg Intake range (mg/1000kcal) <113.2 113.2–148.7 148.7–195.1 ≥195.1 -
Model 1 a 1.00 0.87 (0.65–1.16) 0.80 (0.60–1.08) 0.66 (0.49–0.88) 0.0367
Model 2 b 1.00 0.90 (0.67–1.20) 0.83 (0.61–1.11) 0.66 (0.49–0.88) 0.0405
Model 3 c 1.00 0.92 (0.68–1.24) 0.85 (0.60–1.20) 0.70 (0.47–1.05) 0.3811

HBP: High Blood Pressure

a Model 1: Adjusted for age and BMI (continuous).

b Model 2: Adjusted for education (elementary school or less, middle or high school, college or more), income (quartiles of household income), physical activity (MET), smoking status (never smoker, past smoker, current smoker), and frequency of alcohol (none, <1 time/month, 2~4 times/month, ≥2 times/week) in addition to model 1.

c Model 3: Adjusted for total energy (kcal/day), carbohydrate (%energy), protein (%pro), fat (%energy), fiber (g/1000 kcal), calcium (mg/1000 kcal), sodium (mg/1000 kcal), and potassium (mg/1000 kcal) intakes as continuous variables in addition to model 2.