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Discovery of candidate compound 3. IC50 data generated in VSP-FRET at hNav1.8 in HEK293 cells (in house cell line) with at least three tests on three different assay runs. TTX-S data generated in VSP-FRET in SHSY5Y neuroblastoma cell line expressing hNav1.2, hNav1.3, and hNav1.7.16
