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. 2015 May 11;6(6):707–710. doi: 10.1021/acsmedchemlett.5b00146

Table 1. Diameter of Growth Inhibition Zones (mm) in the Agar Diffusion Antibacterial Susceptibility Assaya.

    5-Cip 5Me 7-Cip 7Me 8-Cip 8Me Cip
1 B.subtilis ATCC 6633 35 0 36 0 39 0 20/24Pc
2 S. aureus SG511 25 0 31 0 33 0 21b
3 M. luteus ATCC10240 19 0 17V 0 28 0 0b
4 M. vaccae IMET10670 37 0 24/30P 0 32/42P 0 23b
5 A. baumannii ATCC17961 18/23P 0 24/30P 0 26/32P 0 18/21Pb
6 P. aeruginosa K799/wt 29/35P 0 22/32P 0 41 0 15c
7 P. aeruginosa K799/61 29/38P 0 31/35P 0 35/42P 0 19/24Pc
8 E. coli X580 33/40P 0 31/37P 0 32/40P 0 23d
9 E. coli DC0 17/21P 0 16/23P 0 21/29P 0 18b
10 E. coli DC2 24 0 23 0 27 0 22b
a

P, unclear inhibition zone/many colonies in the inhibition zone; V, very unclear inhibition zone. Exactly 50 μL of a 0.1 mM solution of each compound dissolved in 1:9 DMSO/MeOH was added to 9 mm wells in agar media (Standard I Nutrient Agar, Serva, or Mueller Hinton II Agar, Becton, Dickinson and Company). Inhibition zones were read after incubation at 37 °C for 24 h. M. vaccae was incubated at 37 °C for 44 h.

b

Ciprofloxacin was tested at 5 μg/mL in H2O.

c

Ciprofloxacin was tested at 1.66 μg/mL in H2O.

d

Ciprofloxacin was tested at 0.33 μg/mL in H2O.