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. 2015 Apr 6;6(6):655–659. doi: 10.1021/acsmedchemlett.5b00071

Figure 2.

Figure 2

(A) H3R2 methylation is induced by 48 h overexpression of PRMT6, but not an empty vector, in A375 cells. (B) PRMT6-induced H3R2 methylation is inhibited by 48 h exposure to EPZ020411 (circles, IC50 = 0.637 ± 0.241 μM) but not by 15 (squares, IC50 > 20 μM).