Table 3. Pharmacokinetic Parameters for EPZ020411 Following i.v. and s.c. Bolus Administration to Sprague-Dawley Rats; Expressed as Mean ± SD, n = 3.

parameter	1 mg/kg i.v.	5 mg/kg s.c.
CL (mL/min/kg)	19.7 ± 1.0
Vss (L/kg)	11.1 ± 1.6
t1/2 (h)	8.54 ± 1.43	9.19 ± 1.60
tmax (h)		0.444
Cmax (ng/mL)		844 ± 306
AUC0-τ (h·ng/mL)	745 ± 34	2456 ± 135
AUC0-inf (h·ng/mL)	846 ± 45	2775 ± 181
F (%)		65.6 ± 4.3