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Hepatic concentrations of DCF, OH-DCF, and DCF-AG in FVB wild-type (WT, ▪) and FVB Mrp3-null (KO, □) mice. Mice were injected with 75 mg/kg DCF. Livers were harvested 90 minutes after administration of vehicle or DCF. Data are expressed as mean ± standard error of the mean for 10–12 subjects/group. *P < 0.05; **P < 0.01 versus WT.
