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. 2015 Apr 22;89(13):6874–6886. doi: 10.1128/JVI.00528-15

TABLE 1.

Highly translated viral mRNAs and their encoded protein function categories at 2, 4, and 8 h post-VACV infection

Time of expression and VACV WR ORFa VACV Copenhagen ORF Temporal expressionb Functional category No. of readsc
2 h
    009/210 C11R E Host interaction 21,247,140
    103 H5R E/Ld Transcription 19,521,388
    18 E Unknown 18,505,965
    59 E3L E Host interaction 16,992,412
    72 I3L E DNA replication 12,105,947
    89 L2R E Virion association 8,753,364
    29 N2L E Host interaction 6,987,681
    200 B19R E Host interaction 6,446,599
    172 A46R E Host interaction 5,931,269
    41 F2L E DNA replication 5,731,347
4 h
    70 I1L I Virion association 31,221,695
    133 A14L L Virion association 27,674,145
    56 F17R L Virion association 18,595,167
    131 A12L I Virion association 17,138,138
    103 H5R E/L Transcription 15,370,215
    132 A13L L Virion association 12,605,197
    139 A19L I Virion association 11,987,935
    137 A17L L Virion association 11,388,463
    28 N1L E/Ld Host interaction 11,342,780
    157 A34R I Virion association 9,677,241
8 h
    133 A14L L Virion association 32,690,917
    70 I1L I Virion association 24,134,410
    167 A42R I Virion association 18,693,389
    56 F17R L Virion association 17,013,444
    131 A12L I Virion association 16,613,835
    28 N1L E/L Host interaction 14,260,755
    103 H5R E/L Transcription 13,848,524
    132 A13L L Virion association 12,915,930
    139 A19L I Virion association 12,450,056
    137 A17L L Virion association 10,427,057
a

For each time period post-VACV infection, the top 10 most highly translated mRNAs are listed.

b

The classification is according to Yang et al. (22, 48). E, early; I, intermediate; L, late.

c

The mRNAs are listed in rank order in terms of the normalized number of reads mapped to the ORF.

d

The L-stage promoter was not distinguished from the intermediate one.

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