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Prolonged c-Fos accumulation occurs during late KSHV lytic replication. (A) 293T and stable KSHV Bac16-harboring 293T cells were induced with 3 mM sodium butyrate (NaB). (B) KSHV-negative SLK- and RTA-inducible rKSHV.219-positive iSLK.219 cells were induced with 1 μg/ml doxycycline (Dox) and 1 mM NaB. At the time points indicated, the cells were collected, lysed, and analyzed by Western blotting.
