FIG 6.

Histological analyses of MGAS5005 infection sites in mice passively immunized with MOPC-21 (A to D) and 2B11 (E and F) MAbs. Three BALB/c mice treated with 2B11 or MOPC-21 were subcutaneously inoculated on the back with 1.0 × 10⁸ CFU of MGAS5005, and the skin samples were collected at 24 h after inoculation. Shown are representative pictures of the Gram- and H&E-stained samples taken at a ×20 magnification. Images in panels A and B are of the inoculation site, and images in panels C and D are of the spread area in MOPC-21-treated mice. No extensive spreading was present in 2B11-treated mice.