Kaplan-Meier analysis of the survival of rats immunized with SAGs (groups B, C, and D) or treated with PBS (group A) and challenged intravenously with S. aureus. Groups: A, nonimmunized control; B, orally immunized; C, subcutaneously immunized; D, intravenously immunized. The asterisks indicate significant differences between the survival rates of the immunized and nonimmunized groups (*, P < 0.05).