FIG 5.

Macrophage phenotype and numbers were analyzed from the joints of Borrelia-infected WT or 5-LOX-deficient mice on days 21 and 56 postinfection. Numbers of F4/80⁺ macrophages (A), M1 (NOS2⁺ CD206⁻) (B), M2 (NOS2⁻ CD206⁺) (C), or rM (NOS2⁺ CD206⁺) (D) were determined. n = 4 for each time point, and the experiment was performed twice. Asterisks indicate data that are significantly different from control data at a P value of <0.05 as determined by ANOVA followed by Dunnett's test.