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Antibody response to PPV23 as a function of CD5− B cell subset. Thirty-three individuals suffering from increased susceptibility to respiratory infections were vaccinated with PPV23. The IgG antibody response to caps-PS serotype 3 (top), caps-PS serotype 4 (middle), and caps-PS serotype 9N (bottom) was measured 3 weeks after vaccination. Shown is the antibody level (y axis) as a function of the number of CD19+ CD5− B cells.
