Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Effect of MEK inhibition by TAK-733 alone and in combination with alisertib on downstream effectors. Effectors of the mitogen activated protein kinase (MAPK) and phosphatidylinositide 3-kinase (PI3K) pathways were evaluated at 24 h. Phosphorylated ERK decreases in all double-mutant CRC cell lines when treated with TAK-733 alone or in combination with alisertib.
