TABLE 1.
Strain | Phenotype | Etest (2-fold dilution) MIC (μg/ml) ofa: |
||
---|---|---|---|---|
TM | SMX | SXT | ||
D457 | Wild type | >32 (128) | 24 (16) | 0.25 (1) |
D457R | D457 overexpressing SmeDEF | >32 (512) | 64 (32) | 2 (8) |
MBS411 | D457 with no SmeE expression | 6 (64) | 24 (16) | 0.190 (0.5) |
TM, trimethoprim; SMX, sulfamethoxazole; SXT, trimethoprim-sulfamethoxazole.