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. 2015 Jun 12;59(7):4003–4011. doi: 10.1128/AAC.04917-14

FIG 3.

FIG 3

Analysis of the generation of reactive oxygen and nitrogen species by nonmelanized and melanized Paracoccidioides yeast cells after aPI. (A to C) Production of ROS (A), NO (B), and ONOO (C). (D) Numbers of CFU/ml after treatment with Tiron (ROS scavenger), l-NAME (NOS inhibitor), and Fetpps (ONOO). *, statistically significant difference in comparison to the control for each aPI treatment (P < 0.0001); #, statistically significant difference in comparison to nonmelanized cells subjected to aPI (P < 0.0001). C, growth control; mel−, nonmelanized cells; mel+, melanized cells. The error bars indicate SEM.